Vai al contenuto

Interazioni tra farmaci

Adenovirus types 4 and 7 live + Mitoxantrone

Gravità: Controindicata

Adenovirus types 4 and 7 live and Mitoxantrone: contraindicated interaction.

Ultimo aggiornamento

Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.

Il contenuto clinico di questa pagina è disponibile solo in inglese.

Sintesi

Mitoxantrone causes myelosuppression and immunosuppression. A live oral adenovirus vaccine could cause disseminated vaccine-virus infection, and the immune response to it will be poor.

Cosa significa questa interazione in parole semplici

Adenovirus types 4 and 7 live and Mitoxantrone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Moderate

Perché avviene

Immunosuppression impairs control of live attenuated virus replication and reduces vaccine immunogenicity.

Cosa fare

Do not give live vaccines during mitoxantrone therapy. Wait at least 3 months after stopping and confirm immune recovery before vaccinating.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Per gli utenti Pro+

Sblocca la pagina completa

Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Adenovirus types 4 and 7 live e Mitoxantrone, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.

Domande frequenti

Can I take Adenovirus types 4 and 7 live with Mitoxantrone?

MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Mitoxantrone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mitoxantrone causes myelosuppression and immunosuppression. A live oral adenovirus vaccine could cause disseminated vaccine-virus infection, and the immune response to it will be poor.

How serious is the interaction between Adenovirus types 4 and 7 live and Mitoxantrone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during mitoxantrone therapy. Wait at least 3 months after stopping and confirm immune recovery before vaccinating.

What other medicines interact with Mitoxantrone?

MediHelp also lists interactions of Mitoxantrone with, for example, Axicabtagene ciloleucel, Belatacept, Brexucabtagene autoleucel. The full list is on the Mitoxantrone page.

Monografie complete, posologie e verifica delle interazioni nell'app MediHelp

Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.

Sfoglia dalla A alla Z · Interazioni tra farmaci

Scarica l'app Accedi