Interazioni tra farmaci
Asenapine + Pheniramine
Gravità: Moderata
Asenapine and Pheniramine: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Pheniramine is a sedating first-generation antihistamine and asenapine is also sedating, so combined use can produce marked drowsiness and impaired alertness. Anticholinergic effects of pheniramine may add to the effects of asenapine in susceptible patients.
Cosa significa questa interazione in parole semplici
Asenapine and Pheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Asenapine belongs to Central Nervous System; Pheniramine belongs to Respiratory.
Perché avviene
Additive CNS depression from H1 antagonism and antipsychotic receptor blockade.
Cosa fare
Counsel patients about sedation and avoid driving or hazardous tasks. Prefer a non-sedating antihistamine if one is needed regularly.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Asenapine e Pheniramine, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 7 giorni sul web. Nessuna carta.
Altre interazioni di Asenapine
- Asenapine + Pimozide Controindicata
- Asenapine + Thioridazine Controindicata
- Asenapine + Vandetanib Controindicata
- Adagrasib + Asenapine Maggiore
- Alfentanil + Asenapine Maggiore
- Alfuzosin + Asenapine Maggiore
Altre interazioni di Pheniramine
- Amisulpride + Pheniramine Moderata
- Brexpiprazole + Pheniramine Moderata
- Brivaracetam + Pheniramine Moderata
- Cariprazine + Pheniramine Moderata
- Fentanyl + Pheniramine Moderata
- Levetiracetam + Pheniramine Moderata
Domande frequenti
Can I take Asenapine with Pheniramine?
MediHelp rates the interaction as moderate. Asenapine and Pheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pheniramine is a sedating first-generation antihistamine and asenapine is also sedating, so combined use can produce marked drowsiness and impaired alertness. Anticholinergic effects of pheniramine may add to the effects of asenapine in susceptible patients.
How serious is the interaction between Asenapine and Pheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about sedation and avoid driving or hazardous tasks. Prefer a non-sedating antihistamine if one is needed regularly.
What other medicines interact with Asenapine?
MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
