Interazioni tra farmaci
Bacitracin-neomycin-polymyxin + Capreomycin
Gravità: Maggiore
Bacitracin-neomycin-polymyxin and Capreomycin: major interaction.
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Sintesi
Capreomycin is nephrotoxic and ototoxic, and neomycin and polymyxin B carry the same risks when absorbed. Combining them can cause additive kidney injury, hearing loss and neuromuscular blockade, especially with large-surface or irrigation use.
Cosa significa questa interazione in parole semplici
Bacitracin-neomycin-polymyxin and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Perché avviene
Additive nephrotoxicity, ototoxicity and neuromuscular blockade from drugs with overlapping toxicity.
Cosa fare
Avoid concurrent systemic or high-absorption use of these agents. If unavoidable, monitor serum creatinine, electrolytes and hearing, and use the shortest possible course.
Cosa chiedere al farmacista
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Altre interazioni di Bacitracin-neomycin-polymyxin
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin Maggiore
- Atracurium + Bacitracin-neomycin-polymyxin Maggiore
- Bacitracin-neomycin-polymyxin + Cidofovir Maggiore
- Bacitracin-neomycin-polymyxin + Cisatracurium Maggiore
- Bacitracin-neomycin-polymyxin + Pancuronium Maggiore
- Bacitracin-neomycin-polymyxin + Rocuronium Maggiore
Domande frequenti
Can I take Bacitracin-neomycin-polymyxin with Capreomycin?
MediHelp rates the interaction as major. Bacitracin-neomycin-polymyxin and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin is nephrotoxic and ototoxic, and neomycin and polymyxin B carry the same risks when absorbed. Combining them can cause additive kidney injury, hearing loss and neuromuscular blockade, especially with large-surface or irrigation use.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Capreomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent systemic or high-absorption use of these agents. If unavoidable, monitor serum creatinine, electrolytes and hearing, and use the shortest possible course.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Cidofovir. The full list is on the Bacitracin-neomycin-polymyxin page.
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