Interazioni tra farmaci
Basiliximab + Bcg vaccine live
Gravità: Controindicata
Basiliximab and Bcg vaccine live: contraindicated interaction.
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Sintesi
BCG is a live attenuated bacterial vaccine that can cause disseminated BCG infection in immunosuppressed patients. Basiliximab also impairs the immune response, so vaccination may not work.
Cosa significa questa interazione in parole semplici
Basiliximab and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
IL-2 receptor blockade suppresses T-cell activation needed to contain live attenuated mycobacteria.
Cosa fare
Do not give BCG to patients receiving basiliximab; use other TB prevention measures and reassess after immune recovery.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Basiliximab
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Controindicata
- Basiliximab + Measles mumps and rubella vaccine Controindicata
- Basiliximab + Measles mumps and rubella vaccine live Controindicata
- Basiliximab + Measles mumps rubella and varicella vaccine live Controindicata
- Basiliximab + Measles vaccine Controindicata
- Basiliximab + Rotavirus oral vaccine live Controindicata
Domande frequenti
Can I take Basiliximab with Bcg vaccine live?
MediHelp rates the interaction as contraindicated. Basiliximab and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated bacterial vaccine that can cause disseminated BCG infection in immunosuppressed patients. Basiliximab also impairs the immune response, so vaccination may not work.
How serious is the interaction between Basiliximab and Bcg vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients receiving basiliximab; use other TB prevention measures and reassess after immune recovery.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Basiliximab page.
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