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Interazioni tra farmaci

Bcg vaccine live + Ethambutol

Gravità: Moderata

Bcg vaccine live and Ethambutol: moderate interaction.

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Sintesi

Ethambutol is active against mycobacteria and could reduce replication of the live BCG strain, potentially lowering vaccine effect. The interaction is largely theoretical, as antimycobacterial drugs generally impair live BCG.

Cosa significa questa interazione in parole semplici

Bcg vaccine live and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Livello di evidenza: Low

Perché avviene

Antimycobacterial activity of ethambutol may inhibit the live attenuated BCG organism.

Cosa fare

Avoid giving BCG vaccine during ethambutol therapy; defer vaccination until after the course is finished.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Bcg vaccine live with Ethambutol?

MediHelp rates the interaction as moderate. Bcg vaccine live and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ethambutol is active against mycobacteria and could reduce replication of the live BCG strain, potentially lowering vaccine effect. The interaction is largely theoretical, as antimycobacterial drugs generally impair live BCG.

How serious is the interaction between Bcg vaccine live and Ethambutol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving BCG vaccine during ethambutol therapy; defer vaccination until after the course is finished.

What other medicines interact with Ethambutol?

MediHelp also lists interactions of Ethambutol with, for example, Allopurinol, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Ethambutol page.

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