Vai al contenuto

Interazioni tra farmaci

Capreomycin + Rocuronium

Gravità: Maggiore

Capreomycin and Rocuronium: major interaction.

Ultimo aggiornamento

Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.

Il contenuto clinico di questa pagina è disponibile solo in inglese.

Sintesi

Capreomycin has neuromuscular blocking activity and can intensify and prolong non-depolarizing blockade from rocuronium. This can result in prolonged paralysis and respiratory insufficiency, especially with renal impairment.

Cosa significa questa interazione in parole semplici

Capreomycin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Livello di evidenza: Moderate

Perché avviene

Additive neuromuscular blockade through intrinsic curare-like effects of capreomycin at the neuromuscular junction.

Cosa fare

Avoid combining when alternatives exist; otherwise reduce rocuronium dose and monitor with train-of-four until full recovery. Have ventilatory support ready and consider renal function.

Cosa chiedere al farmacista

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Per gli utenti Pro+

Sblocca la pagina completa

Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Capreomycin e Rocuronium, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.

Domande frequenti

Can I take Capreomycin with Rocuronium?

MediHelp rates the interaction as major. Capreomycin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has neuromuscular blocking activity and can intensify and prolong non-depolarizing blockade from rocuronium. This can result in prolonged paralysis and respiratory insufficiency, especially with renal impairment.

How serious is the interaction between Capreomycin and Rocuronium?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining when alternatives exist; otherwise reduce rocuronium dose and monitor with train-of-four until full recovery. Have ventilatory support ready and consider renal function.

What other medicines interact with Rocuronium?

MediHelp also lists interactions of Rocuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Clindamycin. The full list is on the Rocuronium page.

Monografie complete, posologie e verifica delle interazioni nell'app MediHelp

Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.

Sfoglia dalla A alla Z · Interazioni tra farmaci

Scarica l'app Accedi