Vai al contenuto

Interazioni tra farmaci

Cefpodoxime + Gentamicin

Gravità: Moderata

Cefpodoxime and Gentamicin: moderate interaction.

Ultimo aggiornamento

Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.

Il contenuto clinico di questa pagina è disponibile solo in inglese.

Sintesi

Cephalosporins have been reported to add to aminoglycoside nephrotoxicity, though oral cefpodoxime has low direct renal toxicity. Risk is higher in patients with kidney impairment, older age, or dehydration.

Cosa significa questa interazione in parole semplici

Cefpodoxime and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefpodoxime belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.

Livello di evidenza: Low

Perché avviene

Possible additive renal tubular injury; cefpodoxime itself is rarely nephrotoxic.

Cosa fare

Monitor serum creatinine and gentamicin levels during co-therapy, and adjust gentamicin dosing to renal function. Maintain hydration.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Per gli utenti Pro+

Sblocca la pagina completa

Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Cefpodoxime e Gentamicin, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.

Domande frequenti

Can I take Cefpodoxime with Gentamicin?

MediHelp rates the interaction as moderate. Cefpodoxime and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephalosporins have been reported to add to aminoglycoside nephrotoxicity, though oral cefpodoxime has low direct renal toxicity. Risk is higher in patients with kidney impairment, older age, or dehydration.

How serious is the interaction between Cefpodoxime and Gentamicin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels during co-therapy, and adjust gentamicin dosing to renal function. Maintain hydration.

What other medicines interact with Cefpodoxime?

MediHelp also lists interactions of Cefpodoxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefpodoxime page.

Monografie complete, posologie e verifica delle interazioni nell'app MediHelp

Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.

Sfoglia dalla A alla Z · Interazioni tra farmaci

Scarica l'app Accedi