Interazioni tra farmaci
Dulaglutide + Empagliflozin-linagliptin
Gravità: Moderata
Dulaglutide and Empagliflozin-linagliptin: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Combining dulaglutide with empagliflozin and linagliptin gives additive glucose lowering. Linagliptin and dulaglutide both act on the incretin pathway, so adding a DPP-4 inhibitor to a GLP-1 agonist offers little extra benefit and adds cost and pill burden.
Cosa significa questa interazione in parole semplici
Dulaglutide and Empagliflozin-linagliptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dulaglutide belongs to Endocrine; Empagliflozin-linagliptin belongs to Endocrine.
Perché avviene
Overlapping incretin-pathway activity plus additive antihyperglycemic effect of SGLT2 inhibition.
Cosa fare
Avoid routine combination of a DPP-4 inhibitor with a GLP-1 agonist. Monitor glucose, volume status and gastrointestinal tolerability.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Dulaglutide e Empagliflozin-linagliptin, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Empagliflozin-linagliptin
Altre interazioni di Dulaglutide
- Dulaglutide + Insulin degludec-liraglutide Maggiore
- Dulaglutide + Insulin glargine-lixisenatide Maggiore
- Alogliptin-metformin + Dulaglutide Moderata
- Alogliptin-pioglitazone + Dulaglutide Moderata
- Alogliptin + Dulaglutide Moderata
- Chlorpropamide + Dulaglutide Moderata
Domande frequenti
Can I take Dulaglutide with Empagliflozin-linagliptin?
MediHelp rates the interaction as moderate. Dulaglutide and Empagliflozin-linagliptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining dulaglutide with empagliflozin and linagliptin gives additive glucose lowering. Linagliptin and dulaglutide both act on the incretin pathway, so adding a DPP-4 inhibitor to a GLP-1 agonist offers little extra benefit and adds cost and pill burden.
How serious is the interaction between Dulaglutide and Empagliflozin-linagliptin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine combination of a DPP-4 inhibitor with a GLP-1 agonist. Monitor glucose, volume status and gastrointestinal tolerability.
What other medicines interact with Empagliflozin-linagliptin?
MediHelp also lists interactions of Empagliflozin-linagliptin with, for example, Fosphenytoin, Rifampin, Rifapentine. The full list is on the Empagliflozin-linagliptin page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
