医薬品リファレンス
Atacicept
Atacicept is a medicine in the class miscellaneous. It is used for nephropathy.
- 薬効分類: Miscellaneous
- 効能・効果: nephropathy
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- 一般的な剤形
- 注射剤
- 一般的な規格
- 150 mg
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
TACI-Fc fusion glycoprotein that binds BAFF (BLyS) and APRIL, reducing BAFF- and APRIL-mediated signaling and decreasing production of galactose-deficient IgA1 (Gd-IgA1), which is implicated in IgAN.
成人の通常用量（添付文書の要約）
Primary IgA nephropathy (to reduce proteinuria): 150 mg subcutaneously once weekly
妊娠と授乳
- 妊娠
- Unknown Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies.
- 授乳
- Unknown No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
報告されている副作用
- Infections
- Upper respiratory tract infection
- Local administration reactions
- Injection site reaction
- Injection site erythema
禁忌
- Serious hypersensitivity to atacicept-vymj or any excipients.
注意が必要な方
- Immunosuppression and increased risk of infections: assess for active infection before starting, monitor during treatment, and consider interruption for serious infection.
- Concomitant use with other immune-modulating drugs, including systemic corticosteroids, may increase infection risk; combined use has not been evaluated.
- May interfere with vaccine responses; complete immunizations before starting; live vaccines not recommended within 30 days before or during treatment.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ataciceptの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
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よくある質問
What is Atacicept used for?
Atacicept is a medicine in the class miscellaneous. It is used for Nephropathy.
What side effects have been reported with Atacicept?
Infections, Upper respiratory tract infection, Local administration reactions, Injection site reaction, Injection site erythema.
Can Atacicept be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies. Breastfeeding: Unknown. No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
What does Atacicept interact with?
MediHelp does not list a checked interaction for Atacicept yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
