医薬品リファレンス
Deucravacitinib
Deucravacitinib is a medicine in the class miscellaneous. It is used for plaque psoriasis.
- 薬効分類: Miscellaneous
- 効能・効果: plaque psoriasis
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- ATCコード
- L04AF07
- 一般的な剤形
- 錠剤
- 一般的な規格
- 6 mg
- 商品名
- 2
- 国・市場
- 2
何に使われるか
作用のしくみ
Allosteric inhibitor of tyrosine kinase 2 (TYK2); binds the regulatory domain, stabilizing an inhibitory interaction with the catalytic domain and inhibiting receptor-mediated TYK2 activation and downstream STAT activation.
成人の通常用量（添付文書の要約）
Plaque psoriasis and psoriatic arthritis: 6 mg orally once daily, with or without food
妊娠と授乳
- 妊娠
- Unknown Case reports are too few to assess risk; no embryo-fetal effects in rats and rabbits at doses at least 72 times the maximum human dose. Use only if the benefit justifies the risk.
- 授乳
- Unknown No human milk data; it is present in rat milk. US label: weigh breastfeeding against the mother's need. No guidance supports routine use; an alternative with more data may be preferred.
報告されている副作用
- Upper respiratory infections
- Blood creatine phosphokinase increased
- Herpes simplex
- Mouth ulcers
- Folliculitis
- Acne
禁忌
- History of hypersensitivity reaction to deucravacitinib or any excipients.
注意が必要な方
- Hypersensitivity reactions such as angioedema have been reported; discontinue if clinically significant reaction occurs.
- May increase risk of infections; avoid in active or serious infection; herpes virus reactivation reported; consider hepatitis screening.
- Evaluate for latent and active TB before starting; do not give to patients with active TB.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Deucravacitinibの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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関連するクイックリード
よくある質問
What is Deucravacitinib used for?
Deucravacitinib is a medicine in the class miscellaneous. It is used for Plaque psoriasis, Psoriatic arthritis.
What side effects have been reported with Deucravacitinib?
Upper respiratory infections, Blood creatine phosphokinase increased, Herpes simplex, Mouth ulcers, Folliculitis, Acne.
Can Deucravacitinib be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Case reports are too few to assess risk; no embryo-fetal effects in rats and rabbits at doses at least 72 times the maximum human dose. Use only if the benefit justifies the risk. Breastfeeding: Unknown. No human milk data; it is present in rat milk. US label: weigh breastfeeding against the mother's need. No guidance supports routine use; an alternative with more data may be preferred.
What does Deucravacitinib interact with?
MediHelp does not list a checked interaction for Deucravacitinib yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
