医薬品リファレンス
Ensifentrine
Ensifentrine is a medicine in the class respiratory. It is used for copd.
- 薬効分類: Respiratory
- 効能・効果: copd
最終更新日 出典: US FDA label
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Respiratory
- 一般的な剤形
- 経口懸濁液
- 一般的な規格
- 3 mg/2.5 ml
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Ensifentrine inhibits the PDE3 and PDE4 enzymes, leading to accumulation of intracellular cAMP and/or cGMP and downstream signaling effects.
成人の通常用量（添付文書の要約）
Maintenance treatment of COPD: 3 mg (one unit-dose ampule) twice daily, morning and evening, by oral inhalation using a standard jet nebulizer with a mouthpiece
妊娠と授乳
- 妊娠
- Unknown Inhaled (nebulised) for COPD. No human pregnancy data. No developmental harm in pregnant rats or rabbits; in rats, very high exposure in males increased embryo loss in their untreated female partners.
- 授乳
- Unknown No data on presence in milk or effects on the infant or milk supply. Weigh breastfeeding benefits against the mother's need for treatment.
報告されている副作用
- Back pain
- Hypertension
- Urinary tract infection
- Diarrhea
禁忌
- Hypersensitivity to ensifentrine or any component of the product.
注意が必要な方
- Not for relief of acute bronchospasm; do not use extra doses for that purpose. Treat acute symptoms with an inhaled short-acting bronchodilator.
- Paradoxical bronchospasm may be life threatening; discontinue immediately, treat with an inhaled short-acting bronchodilator and institute alternative therapy.
- Psychiatric adverse reactions including suicidality were reported; weigh risks and benefits in patients with a history of depression and/or suicidal thoughts or behavior.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
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アカウントを作成してPro+トライアルを始めると、Ensifentrineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
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同じ分類のほかの薬剤
よくある質問
What is Ensifentrine used for?
Ensifentrine is a medicine in the class respiratory. It is used for COPD.
What side effects have been reported with Ensifentrine?
Back pain, Hypertension, Urinary tract infection, Diarrhea.
Can Ensifentrine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Inhaled (nebulised) for COPD. No human pregnancy data. No developmental harm in pregnant rats or rabbits; in rats, very high exposure in males increased embryo loss in their untreated female partners. Breastfeeding: Unknown. No data on presence in milk or effects on the infant or milk supply. Weigh breastfeeding benefits against the mother's need for treatment.
What does Ensifentrine interact with?
MediHelp does not list a checked interaction for Ensifentrine yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
