医薬品リファレンス
Etoricoxib
Etoricoxib is a medicine in the class musculoskeletal. It is used for ankylosing spondylitis.
- 薬効分類: Musculoskeletal
- 効能・効果: ankylosing spondylitis
最終更新日 出典: UK SmPC
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要点
- 薬効分類
- Musculoskeletal
- 一般的な剤形
- 錠剤
- 一般的な規格
- 90 mg, 60 mg, 120 mg
- 既知の相互作用
- 1 (中等度: 1)
- 商品名
- 138
- 国・市場
- 4
何に使われるか
作用のしくみ
Inhibits cyclooxygenase (COX)-2; does not affect COX-1 (at therapeutic concentrations), thereby decreasing formation of prostaglandin synthesis.
成人の通常用量（添付文書の要約）
OA: The recommended dose is 30 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 60 mg once daily may increase efficacy.
妊娠と授乳
- 妊娠
- Unsafe Like other NSAIDs it can harm fetal kidneys (low amniotic fluid) from about 20 weeks and close the ductus arteriosus early in the 3rd trimester. EU labels contraindicate etoricoxib throughout pregnancy: do not use, and stop it if pregnancy occurs.
- 授乳
- Unknown Unknown whether it passes into human milk (it does in rats). Product information: women taking etoricoxib must not breastfeed. Prefer ibuprofen.
報告されている副作用
- Headache
- Nausea
- Dyspepsia
- Arthralgia
- Hypertension
- GI Pain
禁忌
- Hypersensitivity to the active substance or any excipient.
- Active peptic ulceration or active gastro-intestinal bleeding.
- Bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or allergic-type reactions after acetylsalicylic acid or NSAIDs including COX-2 inhibitors.
注意が必要な方
- NSAIDs increase risk of serious gastrointestinal (GI) adverse events, including bleeding, ulceration, and gastric or intestinal perforation, which can be fatal
- NSAIDs may increase risk of serious cardiovascular thrombotic events, myocardial infarction (MI), and stroke, which can be fatal
- Anemia may occur; monitor hemoglobin or hematorcrit in long term treatment patients.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (1)
- Etoricoxib + Venlafaxine Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Etoricoxibの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Etoricoxib used for?
Etoricoxib is a medicine in the class musculoskeletal. It is used for Ankylosing spondylitis, Gouty arthritis, Osteoarthritis, Pain management, Rheumatoid arthritis.
What side effects have been reported with Etoricoxib?
Headache, Nausea, Dyspepsia, Arthralgia, Hypertension, GI Pain.
Can Etoricoxib be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Like other NSAIDs it can harm fetal kidneys (low amniotic fluid) from about 20 weeks and close the ductus arteriosus early in the 3rd trimester. EU labels contraindicate etoricoxib throughout pregnancy: do not use, and stop it if pregnancy occurs. Breastfeeding: Unknown. Unknown whether it passes into human milk (it does in rats). Product information: women taking etoricoxib must not breastfeed. Prefer ibuprofen.
What does Etoricoxib interact with?
MediHelp lists 1 known interactions for Etoricoxib. Moderate: 1. The most serious include Venlafaxine.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
