医薬品リファレンス
Hydroxocobalamin
Hydroxocobalamin is a medicine in the class miscellaneous. It is used for b12 deficiency.
- 薬効分類: Miscellaneous
- 効能・効果: b12 deficiency
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- ATCコード
- V03AB33
- 一般的な剤形
- 注射剤
- 一般的な規格
- 1 mg/ml, 1000 mcg, 1000 mcg/ml
- 商品名
- 19
- 国・市場
- 5
何に使われるか
作用のしくみ
Vitamin B12 with hydroxyl group complexed to cobalt which can be displaced by cyanide resulting in cyanocobalamin that is renally excreted
成人の通常用量（添付文書の要約）
Cyanide Poisoning: 70 mg/kg (usually 5 g) IV infusion over 15 minutes; additional 5 g IV may be given depending on severity of poisoning and clinical response
妊娠と授乳
- 妊娠
- Unknown Vitamin B12 injections for deficiency are safe and needed in pregnancy. Cyanokit (5 g IV antidote for cyanide poisoning): human data insufficient; animal studies showed skeletal and soft-tissue defects at similar exposures. Do not withhold it, as cyanide poisoning is life-threatening.
- 授乳
- Unknown Vitamin B12 injections at usual doses: B12 is a normal milk component; compatible. Cyanokit: present in milk; US label: do not breastfeed during treatment, and no data on when to restart.
報告されている副作用
- Headache
- Nausea
- Increased blood pressure
- Erythema
- Chromaturia
- Decrease in lymphocytes
注意が必要な方
- Substantial increases in blood pressure may occur following therapy; monitor blood pressure during treatment
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Hydroxocobalaminの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Hydroxocobalamin used for?
Hydroxocobalamin is a medicine in the class miscellaneous. It is used for B12 deficiency, Cyanide poisoning.
What side effects have been reported with Hydroxocobalamin?
Headache, Nausea, Increased blood pressure, Erythema, Chromaturia, Decrease in lymphocytes.
Can Hydroxocobalamin be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Vitamin B12 injections for deficiency are safe and needed in pregnancy. Cyanokit (5 g IV antidote for cyanide poisoning): human data insufficient; animal studies showed skeletal and soft-tissue defects at similar exposures. Do not withhold it, as cyanide poisoning is life-threatening. Breastfeeding: Unknown. Vitamin B12 injections at usual doses: B12 is a normal milk component; compatible. Cyanokit: present in milk; US label: do not breastfeed during treatment, and no data on when to restart.
What does Hydroxocobalamin interact with?
MediHelp does not list a checked interaction for Hydroxocobalamin yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
