医薬品リファレンス
Thiopental
Thiopental is a medicine in the class central nervous system. It is used for anesthesia.
- 薬効分類: Central Nervous System
- 効能・効果: anesthesia
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要点
- 薬効分類
- Central Nervous System
- 一般的な剤形
- 注射剤
- 一般的な規格
- 1 g, 0.5 g, 500 mg
- 商品名
- 9
- 国・市場
- 2
何に使われるか
作用のしくみ
Thiopental is a barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
成人の通常用量（添付文書の要約）
A normal adult dose for induction of anaesthesia is 4-6 mg/kg body weight
妊娠と授乳
- 妊娠
- Safe FDA warns that lengthy or repeated general anaesthesia in the 3rd trimester may affect fetal brain development. UK label: can be used in pregnancy without adverse effects (long caesarean use), but only when the benefit outweighs the risk; it crosses the placenta and may depress the newborn.
- 授乳
- Safe Very small amounts pass into milk. UK label: suspend breastfeeding for at least 12 hours or express before induction. LactMed: no waiting period is needed; breastfeed once the mother is alert. With several anaesthetics, follow the most restrictive one; watch for sleepiness.
報告されている副作用
- Somnolence
- Bronchospasm
- Hypotension
- Heart arrythmia
- Myocardia depression
- Delayed wakening
注意が必要な方
- Metoclopramide and droperidol reduce the dose of thiopental sodium required to induce anaesthesia.
- Midazolam potentiates the anaesthetic effects of thiopental sodium.
- Pretreatment with probenecid has been shown to potentiate thiopental sodium anaesthesia.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Thiopentalの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Thiopental used for?
Thiopental is a medicine in the class central nervous system. It is used for Anesthesia.
What side effects have been reported with Thiopental?
Somnolence, Bronchospasm, Hypotension, Heart arrythmia, Myocardia depression, Delayed wakening.
Can Thiopental be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. FDA warns that lengthy or repeated general anaesthesia in the 3rd trimester may affect fetal brain development. UK label: can be used in pregnancy without adverse effects (long caesarean use), but only when the benefit outweighs the risk; it crosses the placenta and may depress the newborn. Breastfeeding: Safe. Very small amounts pass into milk. UK label: suspend breastfeeding for at least 12 hours or express before induction. LactMed: no waiting period is needed; breastfeed once the mother is alert. With several anaesthetics, follow the most restrictive one; watch for sleepiness.
What does Thiopental interact with?
MediHelp does not list a checked interaction for Thiopental yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
