医薬品リファレンス
Viloxazine
Viloxazine is a medicine in the class central nervous system. It is used for adhd.
- 薬効分類: Central Nervous System
- 効能・効果: adhd
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Central Nervous System
- 一般的な剤形
- カプセル剤
- 既知の相互作用
- 1 (中等度: 1)
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
The mechanism in ADHD is unclear; it is thought to act by inhibiting norepinephrine reuptake.
成人の通常用量（添付文書の要約）
ADHD (adults): start 200 mg orally once daily; titrate in 200 mg increments weekly; maximum 600 mg once daily
妊娠と授乳
- 妊娠
- Unsafe Based on animal studies, may cause maternal harm; discontinue when pregnancy is recognized unless benefits outweigh risk. Human data are insufficient.
- 授乳
- Unknown Viloxazine is present in breastmilk at a low level (relative infant dose about 1%). No data on effects on the infant or milk production. Weigh benefits of breastfeeding against maternal need.
報告されている副作用
- Somnolence
- Decreased appetite
- Fatigue
- Nausea
- Vomiting
- Insomnia
警告（枠囲み警告）
- Suicidal thoughts and behaviors: higher rates were reported in ADHD patients treated with Qelbree than with placebo. Closely monitor all patients for clinical worsening and emergence of suicidal thoughts and behaviors.
禁忌
- Concomitant MAOI use, or within 14 days after stopping an MAOI (risk of hypertensive crisis).
- Concomitant sensitive CYP1A2 substrates or CYP1A2 substrates with a narrow therapeutic range.
注意が必要な方
- Suicidal thoughts and behaviors: monitor closely, especially in the first few months and at dosage changes; consider changing therapy or discontinuing if they emerge.
- Can increase heart rate and diastolic blood pressure; assess before starting, after dose increases and periodically.
- May induce manic or mixed episodes in bipolar disorder; screen patients before starting.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (1)
- Melatonin + Viloxazine Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Viloxazineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
関連するクイックリード
よくある質問
What is Viloxazine used for?
Viloxazine is a medicine in the class central nervous system. It is used for ADHD.
What side effects have been reported with Viloxazine?
Somnolence, Decreased appetite, Fatigue, Nausea, Vomiting, Insomnia. Serious warning: Suicidal thoughts and behaviors: higher rates were reported in ADHD patients treated with Qelbree than with placebo.
Can Viloxazine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Based on animal studies, may cause maternal harm; discontinue when pregnancy is recognized unless benefits outweigh risk. Human data are insufficient. Breastfeeding: Unknown. Viloxazine is present in breastmilk at a low level (relative infant dose about 1%). No data on effects on the infant or milk production. Weigh benefits of breastfeeding against maternal need.
What does Viloxazine interact with?
MediHelp lists 1 known interactions for Viloxazine. Moderate: 1. The most serious include Melatonin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
