相互作用
Acarbose + Cortisone
重症度: 中等度
Acarbose and Cortisone: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Systemic corticosteroids such as cortisone raise blood glucose and can offset the glucose-lowering effect of acarbose. Patients with diabetes may experience worsened glycemic control, particularly with prolonged or higher-dose corticosteroid courses.
この相互作用をわかりやすく説明すると
Acarbose and Cortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Corticosteroids increase hepatic gluconeogenesis and cause peripheral insulin resistance, opposing the antihyperglycemic action of acarbose.
対処法
Monitor blood glucose more frequently when starting, increasing or stopping cortisone, and adjust the antidiabetic regimen as needed. Reduce doses again when the corticosteroid is tapered to avoid hypoglycemia.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AcarboseとCortisoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Acarboseのその他の相互作用
よくある質問
Can I take Acarbose with Cortisone?
MediHelp rates the interaction as moderate. Acarbose and Cortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids such as cortisone raise blood glucose and can offset the glucose-lowering effect of acarbose. Patients with diabetes may experience worsened glycemic control, particularly with prolonged or higher-dose corticosteroid courses.
How serious is the interaction between Acarbose and Cortisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when starting, increasing or stopping cortisone, and adjust the antidiabetic regimen as needed. Reduce doses again when the corticosteroid is tapered to avoid hypoglycemia.
What other medicines interact with Acarbose?
MediHelp also lists interactions of Acarbose with, for example, Pramlintide, Asenapine, Bitter melon. The full list is on the Acarbose page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
