相互作用
Acetylsalicylic acid + Tirofiban
重症度: 重大
Acetylsalicylic acid and Tirofiban: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Aspirin with tirofiban increases the risk of bleeding. The combination is used deliberately in acute coronary syndromes and PCI but needs close observation.
この相互作用をわかりやすく説明すると
Acetylsalicylic acid and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Tirofiban belongs to Cardiovascular.
なぜ起こるのか
Aspirin inhibits thromboxane-dependent platelet activation while tirofiban blocks glycoprotein IIb/IIIa receptors, giving additive antiplatelet effect.
対処法
Use only for a clear indication and monitor for bleeding, hemoglobin and platelet count. Minimize invasive procedures and vascular access trauma.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Acetylsalicylic acidとTirofibanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Acetylsalicylic acidのその他の相互作用
Tirofibanのその他の相互作用
よくある質問
Can I take Acetylsalicylic acid with Tirofiban?
MediHelp rates the interaction as major. Acetylsalicylic acid and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Aspirin with tirofiban increases the risk of bleeding. The combination is used deliberately in acute coronary syndromes and PCI but needs close observation.
How serious is the interaction between Acetylsalicylic acid and Tirofiban?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only for a clear indication and monitor for bleeding, hemoglobin and platelet count. Minimize invasive procedures and vascular access trauma.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
