相互作用
Adefovir + Emtricitabine
重症度: 中等度
Adefovir and Emtricitabine: moderate interaction.
最終更新日
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概要
Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.
この相互作用をわかりやすく説明すると
Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Adefovir belongs to Anti Virals; Emtricitabine belongs to Anti Virals.
なぜ起こるのか
Competition for renal tubular secretion and additive effects on renal function.
対処法
Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AdefovirとEmtricitabineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Adefovirのその他の相互作用
Emtricitabineのその他の相互作用
よくある質問
Can I take Adefovir with Emtricitabine?
MediHelp rates the interaction as moderate. Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.
How serious is the interaction between Adefovir and Emtricitabine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.
What other medicines interact with Adefovir?
MediHelp also lists interactions of Adefovir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Amikacin, Amphotericin b. The full list is on the Adefovir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
