相互作用
Allopurinol + Ampicillin
重症度: 中等度
Allopurinol and Ampicillin: moderate interaction.
最終更新日
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概要
Patients taking allopurinol together with ampicillin have a higher reported frequency of skin rash than those taking either drug alone. The rash is generally mild and may be hard to tell apart from allopurinol hypersensitivity, which can occasionally be serious.
この相互作用をわかりやすく説明すると
Allopurinol and Ampicillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Allopurinol belongs to Genitourinary; Ampicillin belongs to Anti Bacterial.
なぜ起こるのか
The mechanism is not established; an additive or synergistic hypersensitivity-type reaction has been proposed.
対処法
Counsel the patient to report any rash promptly and evaluate it carefully for allopurinol hypersensitivity. If a rash appears, stop allopurinol and consider an alternative antibiotic.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AllopurinolとAmpicillinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Allopurinolのその他の相互作用
Ampicillinのその他の相互作用
よくある質問
Can I take Allopurinol with Ampicillin?
MediHelp rates the interaction as moderate. Allopurinol and Ampicillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patients taking allopurinol together with ampicillin have a higher reported frequency of skin rash than those taking either drug alone. The rash is generally mild and may be hard to tell apart from allopurinol hypersensitivity, which can occasionally be serious.
How serious is the interaction between Allopurinol and Ampicillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to report any rash promptly and evaluate it carefully for allopurinol hypersensitivity. If a rash appears, stop allopurinol and consider an alternative antibiotic.
What other medicines interact with Allopurinol?
MediHelp also lists interactions of Allopurinol with, for example, Azathioprine, Didanosine, Mercaptopurine. The full list is on the Allopurinol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
