相互作用
Alprazolam + Ganaxolone
重症度: 中等度
Alprazolam and Ganaxolone: moderate interaction.
最終更新日
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概要
Ganaxolone is a neuroactive steroid with sedating effects, and combined use with alprazolam can add to somnolence, dizziness and respiratory depression.
この相互作用をわかりやすく説明すると
Alprazolam and Ganaxolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alprazolam belongs to Central Nervous System; Ganaxolone belongs to Central Nervous System.
なぜ起こるのか
Additive CNS depression via positive modulation of GABA-A receptors.
対処法
Monitor for excessive sedation and reduce the dose of either drug if somnolence is troublesome. Counsel patients on driving and machinery.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AlprazolamとGanaxoloneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Alprazolamのその他の相互作用
Ganaxoloneのその他の相互作用
よくある質問
Can I take Alprazolam with Ganaxolone?
MediHelp rates the interaction as moderate. Alprazolam and Ganaxolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ganaxolone is a neuroactive steroid with sedating effects, and combined use with alprazolam can add to somnolence, dizziness and respiratory depression.
How serious is the interaction between Alprazolam and Ganaxolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and reduce the dose of either drug if somnolence is troublesome. Counsel patients on driving and machinery.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
