相互作用
Amphotericin b + Cephaloridine
重症度: 重大
Amphotericin b and Cephaloridine: major interaction.
最終更新日
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概要
Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in common use. With amphotericin B, the combined renal tubular injury increases the risk of acute kidney injury.
この相互作用をわかりやすく説明すると
Amphotericin b and Cephaloridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive tubular nephrotoxicity.
対処法
Avoid the combination and choose a less nephrotoxic antibacterial. If it cannot be avoided, monitor renal function and electrolytes closely.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Amphotericin bとCephaloridineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amphotericin bのその他の相互作用
よくある質問
Can I take Amphotericin b with Cephaloridine?
MediHelp rates the interaction as major. Amphotericin b and Cephaloridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in common use. With amphotericin B, the combined renal tubular injury increases the risk of acute kidney injury.
How serious is the interaction between Amphotericin b and Cephaloridine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a less nephrotoxic antibacterial. If it cannot be avoided, monitor renal function and electrolytes closely.
What other medicines interact with Amphotericin b?
MediHelp also lists interactions of Amphotericin b with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Amphotericin b page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
