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相互作用

Anagrelide + Sunitinib

重症度: 重大

Anagrelide and Sunitinib: major interaction.

最終更新日

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概要

Both drugs can prolong the QT interval, so using them together raises the risk of ventricular arrhythmia. Anagrelide can also cause tachycardia and palpitations, which adds to the cardiac risk.

この相互作用をわかりやすく説明すると

Anagrelide and Sunitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Anagrelide belongs to Cardiovascular; Sunitinib belongs to Oncology.

エビデンスレベル: Moderate

なぜ起こるのか

Additive QT prolongation.

対処法

Avoid the combination where possible. If it is needed, monitor ECG and electrolytes closely.

薬剤師に尋ねること

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、AnagrelideとSunitinibの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Anagrelide with Sunitinib?

MediHelp rates the interaction as major. Anagrelide and Sunitinib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can prolong the QT interval, so using them together raises the risk of ventricular arrhythmia. Anagrelide can also cause tachycardia and palpitations, which adds to the cardiac risk.

How serious is the interaction between Anagrelide and Sunitinib?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible. If it is needed, monitor ECG and electrolytes closely.

What other medicines interact with Sunitinib?

MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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