相互作用
Anastrozole + Estrogens esterified
重症度: 併用禁忌
Anastrozole and Estrogens esterified: contraindicated interaction.
最終更新日
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概要
Esterified estrogens provide exogenous estrogen that opposes the estrogen-lowering action of anastrozole. This may reduce its benefit in hormone-sensitive breast cancer.
この相互作用をわかりやすく説明すると
Anastrozole and Estrogens esterified are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Pharmacodynamic antagonism: exogenous estrogen counteracts aromatase inhibition.
対処法
Avoid combining. Use non-hormonal therapies for menopausal symptoms.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AnastrozoleとEstrogens esterifiedの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Anastrozoleのその他の相互作用
よくある質問
Can I take Anastrozole with Estrogens esterified?
MediHelp rates the interaction as contraindicated. Anastrozole and Estrogens esterified are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Esterified estrogens provide exogenous estrogen that opposes the estrogen-lowering action of anastrozole. This may reduce its benefit in hormone-sensitive breast cancer.
How serious is the interaction between Anastrozole and Estrogens esterified?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining. Use non-hormonal therapies for menopausal symptoms.
What other medicines interact with Anastrozole?
MediHelp also lists interactions of Anastrozole with, for example, Bazedoxifene / conjugated estrogens, Bazedoxifene-conjugated estrogens, Conjugated estrogens. The full list is on the Anastrozole page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
