相互作用
Basiliximab + Efgartigimod alfa
重症度: 中等度
Basiliximab and Efgartigimod alfa: moderate interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Efgartigimod blocks the neonatal Fc receptor and speeds clearance of IgG, so IgG-based antibodies such as basiliximab may reach lower exposure. This could reduce the degree of IL-2 receptor blockade during induction.
この相互作用をわかりやすく説明すると
Basiliximab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Efgartigimod alfa belongs to Miscellaneous.
なぜ起こるのか
Blockade of FcRn reduces IgG recycling and increases clearance of IgG monoclonal antibodies.
対処法
Avoid timing efgartigimod cycles around basiliximab doses when possible and monitor for loss of immunosuppressive effect or graft rejection.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BasiliximabとEfgartigimod alfaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Basiliximabのその他の相互作用
- Basiliximab + Bcg vaccine live 併用禁忌
- Basiliximab + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Basiliximab + Measles mumps and rubella vaccine 併用禁忌
- Basiliximab + Measles mumps and rubella vaccine live 併用禁忌
- Basiliximab + Measles mumps rubella and varicella vaccine live 併用禁忌
- Basiliximab + Measles vaccine 併用禁忌
Efgartigimod alfaのその他の相互作用
よくある質問
Can I take Basiliximab with Efgartigimod alfa?
MediHelp rates the interaction as moderate. Basiliximab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Efgartigimod blocks the neonatal Fc receptor and speeds clearance of IgG, so IgG-based antibodies such as basiliximab may reach lower exposure. This could reduce the degree of IL-2 receptor blockade during induction.
How serious is the interaction between Basiliximab and Efgartigimod alfa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid timing efgartigimod cycles around basiliximab doses when possible and monitor for loss of immunosuppressive effect or graft rejection.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
