相互作用
Belimumab + Measles mumps and rubella vaccine
重症度: 重大
Belimumab and Measles mumps and rubella vaccine: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Belimumab is a B-cell survival inhibitor that dampens immune function, so live vaccine viruses may replicate more and the vaccine response may be reduced. Labeling advises against live vaccines with belimumab.
この相互作用をわかりやすく説明すると
Belimumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Belimumab belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
なぜ起こるのか
Inhibition of BLyS reduces B-cell activity, which may blunt vaccine response and impair control of live attenuated viruses.
対処法
Do not give live vaccines within the 30 days before or during belimumab therapy. Update vaccinations beforehand.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BelimumabとMeasles mumps and rubella vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Measles mumps and rubella vaccineのその他の相互作用
- Adalimumab + Measles mumps and rubella vaccine 併用禁忌
- Anakinra + Measles mumps and rubella vaccine 併用禁忌
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 併用禁忌
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 併用禁忌
- Azathioprine + Measles mumps and rubella vaccine 併用禁忌
- Basiliximab + Measles mumps and rubella vaccine 併用禁忌
Belimumabのその他の相互作用
よくある質問
Can I take Belimumab with Measles mumps and rubella vaccine?
MediHelp rates the interaction as major. Belimumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Belimumab is a B-cell survival inhibitor that dampens immune function, so live vaccine viruses may replicate more and the vaccine response may be reduced. Labeling advises against live vaccines with belimumab.
How serious is the interaction between Belimumab and Measles mumps and rubella vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines within the 30 days before or during belimumab therapy. Update vaccinations beforehand.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
