相互作用
Benzhydrocodone / acetaminophen + Cisatracurium
重症度: 重大
Benzhydrocodone / acetaminophen and Cisatracurium: major interaction.
最終更新日
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概要
Opioids combined with neuromuscular blockers can add to respiratory compromise, and opioid sedation may mask inadequate ventilation. The risk arises when residual blockade overlaps with opioid-induced respiratory depression.
この相互作用をわかりやすく説明すると
Benzhydrocodone / acetaminophen and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive respiratory depression: central opioid-mediated depression plus peripheral neuromuscular blockade.
対処法
Use only with controlled ventilation and monitor neuromuscular blockade and respiratory status until full recovery. Use the lowest effective opioid dose and duration.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Benzhydrocodone / acetaminophenとCisatracuriumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cisatracuriumのその他の相互作用
よくある質問
Can I take Benzhydrocodone / acetaminophen with Cisatracurium?
MediHelp rates the interaction as major. Benzhydrocodone / acetaminophen and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with neuromuscular blockers can add to respiratory compromise, and opioid sedation may mask inadequate ventilation. The risk arises when residual blockade overlaps with opioid-induced respiratory depression.
How serious is the interaction between Benzhydrocodone / acetaminophen and Cisatracurium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only with controlled ventilation and monitor neuromuscular blockade and respiratory status until full recovery. Use the lowest effective opioid dose and duration.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Cisatracurium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
