相互作用
Benzphetamine + Phenelzine
重症度: 併用禁忌
Benzphetamine and Phenelzine: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Benzphetamine is a sympathomimetic anorectic, and with MAO inhibitors it can trigger hypertensive crisis. Headache, severe hypertension, and intracranial hemorrhage are possible.
この相互作用をわかりやすく説明すると
Benzphetamine and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
MAO inhibition allows accumulation of norepinephrine, which is released by benzphetamine, producing excessive pressor response.
対処法
Do not use together or within 14 days of stopping phenelzine. Use a non-sympathomimetic weight management approach.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BenzphetamineとPhenelzineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Phenelzineのその他の相互作用
よくある質問
Can I take Benzphetamine with Phenelzine?
MediHelp rates the interaction as contraindicated. Benzphetamine and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Benzphetamine is a sympathomimetic anorectic, and with MAO inhibitors it can trigger hypertensive crisis. Headache, severe hypertension, and intracranial hemorrhage are possible.
How serious is the interaction between Benzphetamine and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 14 days of stopping phenelzine. Use a non-sympathomimetic weight management approach.
What other medicines interact with Phenelzine?
MediHelp also lists interactions of Phenelzine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Phenelzine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。