相互作用
Cyclosporine + Upadacitinib
重症度: 併用禁忌
Cyclosporine and Upadacitinib: contraindicated interaction.
最終更新日
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概要
Cyclosporine is a potent immunosuppressant, and combined with upadacitinib it increases the risk of serious infection and malignancy. Upadacitinib labeling advises against use with potent immunosuppressants such as cyclosporine.
この相互作用をわかりやすく説明すると
Cyclosporine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive immunosuppression through calcineurin and JAK inhibition.
対処法
Avoid the combination. Choose a regimen that does not pair a JAK inhibitor with cyclosporine.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CyclosporineとUpadacitinibの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Upadacitinibのその他の相互作用
よくある質問
Can I take Cyclosporine with Upadacitinib?
MediHelp rates the interaction as contraindicated. Cyclosporine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cyclosporine is a potent immunosuppressant, and combined with upadacitinib it increases the risk of serious infection and malignancy. Upadacitinib labeling advises against use with potent immunosuppressants such as cyclosporine.
How serious is the interaction between Cyclosporine and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. Choose a regimen that does not pair a JAK inhibitor with cyclosporine.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
