相互作用
Hydrocortisone + Smallpox vaccine live
重症度: 併用禁忌
Hydrocortisone and Smallpox vaccine live: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.
この相互作用をわかりやすく説明すると
Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Corticosteroid-induced immunosuppression allows uncontrolled replication of live vaccinia virus.
対処法
Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、HydrocortisoneとSmallpox vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Hydrocortisoneのその他の相互作用
よくある質問
Can I take Hydrocortisone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.
How serious is the interaction between Hydrocortisone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
