相互作用
Ifosfamide + Measles mumps and rubella vaccine
重症度: 併用禁忌
Ifosfamide and Measles mumps and rubella vaccine: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
この相互作用をわかりやすく説明すると
Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.
なぜ起こるのか
Immunosuppression permits replication of live attenuated vaccine viruses: myelosuppression and lymphocyte depletion
対処法
Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、IfosfamideとMeasles mumps and rubella vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Measles mumps and rubella vaccineのその他の相互作用
- Adalimumab + Measles mumps and rubella vaccine 併用禁忌
- Anakinra + Measles mumps and rubella vaccine 併用禁忌
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 併用禁忌
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 併用禁忌
- Azathioprine + Measles mumps and rubella vaccine 併用禁忌
- Basiliximab + Measles mumps and rubella vaccine 併用禁忌
Ifosfamideのその他の相互作用
よくある質問
Can I take Ifosfamide with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
How serious is the interaction between Ifosfamide and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
