Referência de medicamentos
Atacicept
Atacicept is a medicine in the class miscellaneous. It is used for nephropathy.
- Classe do medicamento: Miscellaneous
- Indicado para: nephropathy
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Miscellaneous
- Formas farmacêuticas comuns
- injeção
- Concentrações comuns
- 150 mg
- Nomes comerciais
- 1
- Países e mercados
- 1
Para que é usado
Como funciona
TACI-Fc fusion glycoprotein that binds BAFF (BLyS) and APRIL, reducing BAFF- and APRIL-mediated signaling and decreasing production of galactose-deficient IgA1 (Gd-IgA1), which is implicated in IgAN.
Dose habitual em adultos (resumo da bula)
Primary IgA nephropathy (to reduce proteinuria): 150 mg subcutaneously once weekly
Gravidez e amamentação
- Gravidez
- Unknown Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies.
- Amamentação
- Unknown No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
Efeitos adversos relatados
- Infections
- Upper respiratory tract infection
- Local administration reactions
- Injection site reaction
- Injection site erythema
Contraindicações
- Serious hypersensitivity to atacicept-vymj or any excipients.
Quem deve ter cuidado
- Immunosuppression and increased risk of infections: assess for active infection before starting, monitor during treatment, and consider interruption for serious infection.
- Concomitant use with other immune-modulating drugs, including systemic corticosteroids, may increase infection risk; combined use has not been evaluated.
- May interfere with vaccine responses; complete immunizations before starting; live vaccines not recommended within 30 days before or during treatment.
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
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Perguntas frequentes
What is Atacicept used for?
Atacicept is a medicine in the class miscellaneous. It is used for Nephropathy.
What side effects have been reported with Atacicept?
Infections, Upper respiratory tract infection, Local administration reactions, Injection site reaction, Injection site erythema.
Can Atacicept be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies. Breastfeeding: Unknown. No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
What does Atacicept interact with?
MediHelp does not list a checked interaction for Atacicept yet. Always tell your pharmacist about every medicine you take.
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