Interações medicamentosas
Acetaminophen / phenyltoloxamine + Levetiracetam
Gravidade: Moderada
Acetaminophen / phenyltoloxamine and Levetiracetam: moderate interaction.
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Resumo
Phenyltoloxamine is a sedating first-generation antihistamine, and levetiracetam also causes somnolence and dizziness. Together they may increase drowsiness and impair psychomotor performance.
O que esta interação significa em palavras simples
Acetaminophen / phenyltoloxamine and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive CNS depression from the sedating antihistamine and levetiracetam.
O que fazer
Warn patients about drowsiness and avoid driving or hazardous tasks until the response is known. Avoid alcohol and consider a non-sedating alternative.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Levetiracetam
Perguntas frequentes
Can I take Acetaminophen / phenyltoloxamine with Levetiracetam?
MediHelp rates the interaction as moderate. Acetaminophen / phenyltoloxamine and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phenyltoloxamine is a sedating first-generation antihistamine, and levetiracetam also causes somnolence and dizziness. Together they may increase drowsiness and impair psychomotor performance.
How serious is the interaction between Acetaminophen / phenyltoloxamine and Levetiracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn patients about drowsiness and avoid driving or hazardous tasks until the response is known. Avoid alcohol and consider a non-sedating alternative.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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