Interações medicamentosas
Acetylsalicylic acid + Tirofiban
Gravidade: Grave
Acetylsalicylic acid and Tirofiban: major interaction.
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Aspirin with tirofiban increases the risk of bleeding. The combination is used deliberately in acute coronary syndromes and PCI but needs close observation.
O que esta interação significa em palavras simples
Acetylsalicylic acid and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Tirofiban belongs to Cardiovascular.
Por que acontece
Aspirin inhibits thromboxane-dependent platelet activation while tirofiban blocks glycoprotein IIb/IIIa receptors, giving additive antiplatelet effect.
O que fazer
Use only for a clear indication and monitor for bleeding, hemoglobin and platelet count. Minimize invasive procedures and vascular access trauma.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Referências
Outras interações de Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicada
- Acetylsalicylic acid + Ketorolac intranasal Contraindicada
- Abciximab + Acetylsalicylic acid Grave
- Acemetacin + Acetylsalicylic acid Grave
- Acetazolamide + Acetylsalicylic acid Grave
- Acetylsalicylic acid + Alteplase Grave
Outras interações de Tirofiban
Perguntas frequentes
Can I take Acetylsalicylic acid with Tirofiban?
MediHelp rates the interaction as major. Acetylsalicylic acid and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Aspirin with tirofiban increases the risk of bleeding. The combination is used deliberately in acute coronary syndromes and PCI but needs close observation.
How serious is the interaction between Acetylsalicylic acid and Tirofiban?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only for a clear indication and monitor for bleeding, hemoglobin and platelet count. Minimize invasive procedures and vascular access trauma.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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