Interações medicamentosas
Aclidinium + Trospium
Gravidade: Moderada
Aclidinium and Trospium: moderate interaction.
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Resumo
Both are antimuscarinics, and inhaled aclidinium has low systemic absorption. Combined use may still add to dry mouth, constipation and urinary retention, and the combination may worsen glaucoma or bladder outlet obstruction.
O que esta interação significa em palavras simples
Aclidinium and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive antimuscarinic effects.
O que fazer
Monitor for urinary retention, constipation and worsening of narrow-angle glaucoma. Avoid the combination in patients with these conditions.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Trospium
- Clozapine + Trospium Grave
- Pramlintide + Trospium Grave
- Thioridazine + Trospium Grave
- Trihexyphenidyl + Trospium Grave
- Amantadine + Trospium Moderada
- Amitriptyline + Trospium Moderada
Perguntas frequentes
Can I take Aclidinium with Trospium?
MediHelp rates the interaction as moderate. Aclidinium and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinics, and inhaled aclidinium has low systemic absorption. Combined use may still add to dry mouth, constipation and urinary retention, and the combination may worsen glaucoma or bladder outlet obstruction.
How serious is the interaction between Aclidinium and Trospium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation and worsening of narrow-angle glaucoma. Avoid the combination in patients with these conditions.
What other medicines interact with Trospium?
MediHelp also lists interactions of Trospium with, for example, Clozapine, Pramlintide, Thioridazine. The full list is on the Trospium page.
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