Interações medicamentosas
Adefovir + Emtricitabine
Gravidade: Moderada
Adefovir and Emtricitabine: moderate interaction.
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Resumo
Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.
O que esta interação significa em palavras simples
Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Adefovir belongs to Anti Virals; Emtricitabine belongs to Anti Virals.
Por que acontece
Competition for renal tubular secretion and additive effects on renal function.
O que fazer
Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Adefovir
Outras interações de Emtricitabine
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Emtricitabine Contraindicada
- Atidarsagene autotemcel + Emtricitabine Grave
- Betibeglogene autotemcel + Emtricitabine Grave
- Elivaldogene autotemcel + Emtricitabine Grave
- Emtricitabine + Lamivudine Grave
- Emtricitabine + Lovotibeglogene autotemcel Grave
Perguntas frequentes
Can I take Adefovir with Emtricitabine?
MediHelp rates the interaction as moderate. Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.
How serious is the interaction between Adefovir and Emtricitabine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.
What other medicines interact with Adefovir?
MediHelp also lists interactions of Adefovir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Amikacin, Amphotericin b. The full list is on the Adefovir page.
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