Pular para o conteúdo

Interações medicamentosas

Adefovir + Emtricitabine

Gravidade: Moderada

Adefovir and Emtricitabine: moderate interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.

O que esta interação significa em palavras simples

Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Adefovir belongs to Anti Virals; Emtricitabine belongs to Anti Virals.

Nível de evidência: Low

Por que acontece

Competition for renal tubular secretion and additive effects on renal function.

O que fazer

Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Para assinantes do Pro+

Desbloqueie a página completa

Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Adefovir e Emtricitabine, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Experimente o Pro+ grátis por 14 dias na web. Sem cartão.

Perguntas frequentes

Can I take Adefovir with Emtricitabine?

MediHelp rates the interaction as moderate. Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.

How serious is the interaction between Adefovir and Emtricitabine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.

What other medicines interact with Adefovir?

MediHelp also lists interactions of Adefovir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Amikacin, Amphotericin b. The full list is on the Adefovir page.

Monografias completas, posologia e verificador de interações no app MediHelp

Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.

Explorar de A a Z · Interações medicamentosas

Baixar o app Entrar