Interações medicamentosas
Adenovirus types 4 and 7 live + Epirubicin
Gravidade: Contraindicada
Adenovirus types 4 and 7 live and Epirubicin: contraindicated interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Epirubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The vaccine strains may also replicate more than intended in an immunocompromised patient, leading to vaccine-related infection.
O que esta interação significa em palavras simples
Adenovirus types 4 and 7 live and Epirubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Cytotoxic immunosuppression impairs the immune response and permits uncontrolled replication of live attenuated virus.
O que fazer
Do not give live vaccines during chemotherapy; defer vaccination until immune recovery, usually at least 3 months after treatment ends. Use non-live vaccines where available.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Epirubicin
- Belatacept + Epirubicin Grave
- Cimetidine + Epirubicin Grave
- Deferiprone + Epirubicin Grave
- Dengue vaccine + Epirubicin Grave
- Epirubicin + Etrasimod Grave
- Epirubicin + Fingolimod Grave
Perguntas frequentes
Can I take Adenovirus types 4 and 7 live with Epirubicin?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Epirubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Epirubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The vaccine strains may also replicate more than intended in an immunocompromised patient, leading to vaccine-related infection.
How serious is the interaction between Adenovirus types 4 and 7 live and Epirubicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; defer vaccination until immune recovery, usually at least 3 months after treatment ends. Use non-live vaccines where available.
What other medicines interact with Epirubicin?
MediHelp also lists interactions of Epirubicin with, for example, Belatacept, Cimetidine, Deferiprone. The full list is on the Epirubicin page.
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