Interações medicamentosas
Adenovirus types 4 and 7 live + Idarubicin
Gravidade: Contraindicada
Adenovirus types 4 and 7 live and Idarubicin: contraindicated interaction.
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Resumo
Idarubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The vaccine strains may also replicate more than intended in an immunocompromised patient, leading to vaccine-related infection.
O que esta interação significa em palavras simples
Adenovirus types 4 and 7 live and Idarubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Cytotoxic immunosuppression impairs the immune response and permits uncontrolled replication of live attenuated virus.
O que fazer
Do not give live vaccines during chemotherapy; defer vaccination until immune recovery, usually at least 3 months after treatment ends. Use non-live vaccines where available.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Idarubicin
Perguntas frequentes
Can I take Adenovirus types 4 and 7 live with Idarubicin?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Idarubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Idarubicin causes myelosuppression and immunosuppression, which can blunt the response to the live oral adenovirus vaccine. The vaccine strains may also replicate more than intended in an immunocompromised patient, leading to vaccine-related infection.
How serious is the interaction between Adenovirus types 4 and 7 live and Idarubicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; defer vaccination until immune recovery, usually at least 3 months after treatment ends. Use non-live vaccines where available.
What other medicines interact with Idarubicin?
MediHelp also lists interactions of Idarubicin with, for example, Belatacept, Cyclophosphamide, Deferiprone. The full list is on the Idarubicin page.
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