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Interações medicamentosas

Alendronate + Sucroferric oxyhydroxide

Gravidade: Moderada

Alendronate and Sucroferric oxyhydroxide: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Sucroferric oxyhydroxide is a phosphate binder containing iron that can bind alendronate in the gut. This lowers alendronate absorption and may reduce its efficacy.

O que esta interação significa em palavras simples

Alendronate and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Alendronate belongs to Musculoskeletal; Sucroferric oxyhydroxide belongs to Genitourinary.

Nível de evidência: Moderate

Por que acontece

Binding or chelation of alendronate by iron-containing phosphate binder in the GI tract reduces absorption.

O que fazer

Take alendronate with plain water at least 1 hour before sucroferric oxyhydroxide, and never at the same time.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Alendronate with Sucroferric oxyhydroxide?

MediHelp rates the interaction as moderate. Alendronate and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sucroferric oxyhydroxide is a phosphate binder containing iron that can bind alendronate in the gut. This lowers alendronate absorption and may reduce its efficacy.

How serious is the interaction between Alendronate and Sucroferric oxyhydroxide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take alendronate with plain water at least 1 hour before sucroferric oxyhydroxide, and never at the same time.

What other medicines interact with Alendronate?

MediHelp also lists interactions of Alendronate with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Alendronate page.

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