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Interações medicamentosas

Alprazolam + Lasmiditan

Gravidade: Moderada

Alprazolam and Lasmiditan: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Lasmiditan commonly causes dizziness and sedation, and alprazolam is a sedating benzodiazepine. Taken together they may produce additive drowsiness and impaired psychomotor and cognitive performance. This combination has not been formally studied.

O que esta interação significa em palavras simples

Alprazolam and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Alprazolam belongs to Central Nervous System; Lasmiditan belongs to Central Nervous System.

Nível de evidência: Low

Por que acontece

Additive central nervous system depression through pharmacodynamic synergism.

O que fazer

Counsel the patient to avoid driving or operating machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation and reduce doses if it occurs.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Alprazolam with Lasmiditan?

MediHelp rates the interaction as moderate. Alprazolam and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan commonly causes dizziness and sedation, and alprazolam is a sedating benzodiazepine. Taken together they may produce additive drowsiness and impaired psychomotor and cognitive performance. This combination has not been formally studied.

How serious is the interaction between Alprazolam and Lasmiditan?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to avoid driving or operating machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation and reduce doses if it occurs.

What other medicines interact with Alprazolam?

MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.

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