Interações medicamentosas
Amikacin + Cefuroxime
Gravidade: Moderada
Amikacin and Cefuroxime: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Cefuroxime given with amikacin may increase the risk of kidney injury, especially in older, dehydrated or renally impaired patients. Amikacin is the principal nephrotoxic and ototoxic agent, and the combination is often used on purpose in serious infections.
O que esta interação significa em palavras simples
Amikacin and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefuroxime belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxic potential; cephalosporins may modestly add to aminoglycoside tubular injury.
O que fazer
Monitor serum creatinine and amikacin levels, keep the patient hydrated and limit the aminoglycoside duration. Adjust the doses for renal function.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefuroxime
- Aluminum hydroxide + Cefuroxime Moderada
- Bcg vaccine live + Cefuroxime Moderada
- Calcium carbonate + Cefuroxime Moderada
- Calcium + Cefuroxime Moderada
- Cefuroxime + Cholera vaccine Moderada
- Cefuroxime + Cimetidine Moderada
Outras interações de Amikacin
- Amikacin + Cidofovir Contraindicada
- Adefovir + Amikacin Grave
- Amikacin + Amphotericin b Grave
- Amikacin + Amphotericin b deoxycholate Grave
- Amikacin + Atracurium Grave
- Amikacin + Bacitracin Grave
Perguntas frequentes
Can I take Amikacin with Cefuroxime?
MediHelp rates the interaction as moderate. Amikacin and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefuroxime given with amikacin may increase the risk of kidney injury, especially in older, dehydrated or renally impaired patients. Amikacin is the principal nephrotoxic and ototoxic agent, and the combination is often used on purpose in serious infections.
How serious is the interaction between Amikacin and Cefuroxime?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin levels, keep the patient hydrated and limit the aminoglycoside duration. Adjust the doses for renal function.
What other medicines interact with Cefuroxime?
MediHelp also lists interactions of Cefuroxime with, for example, Aluminum hydroxide, Bcg vaccine live, Calcium carbonate. The full list is on the Cefuroxime page.
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