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Interações medicamentosas

Anakinra + Bcg vaccine live

Gravidade: Contraindicada

Anakinra and Bcg vaccine live: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

BCG contains live attenuated mycobacteria that may cause disseminated BCG infection in patients receiving immunosuppressive biologics such as anakinra. Vaccine effectiveness may also be reduced.

O que esta interação significa em palavras simples

Anakinra and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Low

Por que acontece

Immunosuppression impairs control of replicating attenuated mycobacteria.

O que fazer

Avoid live BCG during anakinra treatment; vaccinate before starting therapy, allowing an adequate interval, if it is required.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Anakinra with Bcg vaccine live?

MediHelp rates the interaction as contraindicated. Anakinra and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG contains live attenuated mycobacteria that may cause disseminated BCG infection in patients receiving immunosuppressive biologics such as anakinra. Vaccine effectiveness may also be reduced.

How serious is the interaction between Anakinra and Bcg vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG during anakinra treatment; vaccinate before starting therapy, allowing an adequate interval, if it is required.

What other medicines interact with Anakinra?

MediHelp also lists interactions of Anakinra with, for example, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Anakinra page.

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