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Interações medicamentosas

Arformoterol + Desipramine

Gravidade: Grave

Arformoterol and Desipramine: major interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.

O que esta interação significa em palavras simples

Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Arformoterol belongs to Respiratory; Desipramine belongs to Central Nervous System.

Nível de evidência: Moderate

Por que acontece

Additive adrenergic stimulation and QT prolongation.

O que fazer

Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Arformoterol with Desipramine?

MediHelp rates the interaction as major. Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.

How serious is the interaction between Arformoterol and Desipramine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.

What other medicines interact with Desipramine?

MediHelp also lists interactions of Desipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Desipramine page.

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