Interações medicamentosas
Arformoterol + Desipramine
Gravidade: Grave
Arformoterol and Desipramine: major interaction.
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Resumo
Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.
O que esta interação significa em palavras simples
Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Desipramine belongs to Central Nervous System.
Por que acontece
Additive adrenergic stimulation and QT prolongation.
O que fazer
Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Desipramine
- Desipramine + Disopyramide Contraindicada
- Desipramine + Dofetilide Contraindicada
- Desipramine + Ibutilide Contraindicada
- Desipramine + Isocarboxazid Contraindicada
- Desipramine + Methylene blue Contraindicada
- Desipramine + Pentamidine Contraindicada
Outras interações de Arformoterol
Perguntas frequentes
Can I take Arformoterol with Desipramine?
MediHelp rates the interaction as major. Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.
How serious is the interaction between Arformoterol and Desipramine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.
What other medicines interact with Desipramine?
MediHelp also lists interactions of Desipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Desipramine page.
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