Interações medicamentosas
Artemether / lumefantrine + Octreotide
Gravidade: Grave
Artemether / lumefantrine and Octreotide: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Artemether/lumefantrine is known to prolong the QT interval, and octreotide may add to this through bradycardia and repolarization effects. Together they may increase the risk of serious ventricular arrhythmias.
O que esta interação significa em palavras simples
Artemether / lumefantrine and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Additive QTc prolongation.
O que fazer
Avoid the combination if feasible; if malaria treatment is essential, obtain an ECG, correct electrolytes and monitor for arrhythmia.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Artemether / lumefantrine e Octreotide, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Octreotide
Perguntas frequentes
Can I take Artemether / lumefantrine with Octreotide?
MediHelp rates the interaction as major. Artemether / lumefantrine and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Artemether/lumefantrine is known to prolong the QT interval, and octreotide may add to this through bradycardia and repolarization effects. Together they may increase the risk of serious ventricular arrhythmias.
How serious is the interaction between Artemether / lumefantrine and Octreotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if feasible; if malaria treatment is essential, obtain an ECG, correct electrolytes and monitor for arrhythmia.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
