Interações medicamentosas
Atenolol-chlorthalidone + Calcium acetate
Gravidade: Moderada
Atenolol-chlorthalidone and Calcium acetate: moderate interaction.
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Resumo
Calcium salts can reduce atenolol absorption in the gut, which may lessen its effect on heart rate and blood pressure. Chlorthalidone also reduces urinary calcium excretion, so calcium load can add to hypercalcaemia risk.
O que esta interação significa em palavras simples
Atenolol-chlorthalidone and Calcium acetate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Calcium acetate belongs to Genitourinary.
Por que acontece
Calcium may bind atenolol or otherwise reduce its gastrointestinal absorption, and thiazides reduce renal calcium excretion.
O que fazer
Separate atenolol and calcium acetate by at least 2 hours. Monitor serum calcium and blood pressure.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Atenolol-chlorthalidone
Outras interações de Calcium acetate
Perguntas frequentes
Can I take Atenolol-chlorthalidone with Calcium acetate?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Calcium acetate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium salts can reduce atenolol absorption in the gut, which may lessen its effect on heart rate and blood pressure. Chlorthalidone also reduces urinary calcium excretion, so calcium load can add to hypercalcaemia risk.
How serious is the interaction between Atenolol-chlorthalidone and Calcium acetate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate atenolol and calcium acetate by at least 2 hours. Monitor serum calcium and blood pressure.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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