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Interações medicamentosas

Atropine + Dicyclomine

Gravidade: Moderada

Atropine and Dicyclomine: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.

O que esta interação significa em palavras simples

Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Atropine belongs to Miscellaneous; Dicyclomine belongs to Respiratory.

Nível de evidência: Moderate

Por que acontece

Additive blockade of muscarinic acetylcholine receptors.

O que fazer

Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Atropine with Dicyclomine?

MediHelp rates the interaction as moderate. Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.

How serious is the interaction between Atropine and Dicyclomine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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