Interações medicamentosas
Basiliximab + Efgartigimod alfa
Gravidade: Moderada
Basiliximab and Efgartigimod alfa: moderate interaction.
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Resumo
Efgartigimod blocks the neonatal Fc receptor and speeds clearance of IgG, so IgG-based antibodies such as basiliximab may reach lower exposure. This could reduce the degree of IL-2 receptor blockade during induction.
O que esta interação significa em palavras simples
Basiliximab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Efgartigimod alfa belongs to Miscellaneous.
Por que acontece
Blockade of FcRn reduces IgG recycling and increases clearance of IgG monoclonal antibodies.
O que fazer
Avoid timing efgartigimod cycles around basiliximab doses when possible and monitor for loss of immunosuppressive effect or graft rejection.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Basiliximab
- Basiliximab + Bcg vaccine live Contraindicada
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Basiliximab + Measles mumps and rubella vaccine Contraindicada
- Basiliximab + Measles mumps and rubella vaccine live Contraindicada
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicada
- Basiliximab + Measles vaccine Contraindicada
Outras interações de Efgartigimod alfa
- Adalimumab + Efgartigimod alfa Moderada
- Ado-trastuzumab + Efgartigimod alfa Moderada
- Bevacizumab + Efgartigimod alfa Moderada
- Brentuximab + Efgartigimod alfa Moderada
- Denosumab + Efgartigimod alfa Moderada
- Efgartigimod alfa + Galcanezumab Moderada
Perguntas frequentes
Can I take Basiliximab with Efgartigimod alfa?
MediHelp rates the interaction as moderate. Basiliximab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Efgartigimod blocks the neonatal Fc receptor and speeds clearance of IgG, so IgG-based antibodies such as basiliximab may reach lower exposure. This could reduce the degree of IL-2 receptor blockade during induction.
How serious is the interaction between Basiliximab and Efgartigimod alfa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid timing efgartigimod cycles around basiliximab doses when possible and monitor for loss of immunosuppressive effect or graft rejection.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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