Interações medicamentosas
Capecitabine + Dengue vaccine
Gravidade: Grave
Capecitabine and Dengue vaccine: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Dengue vaccine is a live attenuated vaccine, and capecitabine-induced immunosuppression may both reduce the immune response and increase the risk of vaccine-related infection. Vaccination during chemotherapy is generally inappropriate.
O que esta interação significa em palavras simples
Capecitabine and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Cytotoxic immunosuppression impairs response to the vaccine and permits replication of live attenuated virus.
O que fazer
Avoid live vaccines during chemotherapy and give them only after immune recovery as advised by the specialist team.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Capecitabine
Perguntas frequentes
Can I take Capecitabine with Dengue vaccine?
MediHelp rates the interaction as major. Capecitabine and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is a live attenuated vaccine, and capecitabine-induced immunosuppression may both reduce the immune response and increase the risk of vaccine-related infection. Vaccination during chemotherapy is generally inappropriate.
How serious is the interaction between Capecitabine and Dengue vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and give them only after immune recovery as advised by the specialist team.
What other medicines interact with Capecitabine?
MediHelp also lists interactions of Capecitabine with, for example, Adenovirus types 4 and 7 live, Arsenic trioxide, Axicabtagene ciloleucel. The full list is on the Capecitabine page.
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