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Interações medicamentosas

Carbidopa-levodopa + Ferric maltol

Gravidade: Moderada

Carbidopa-levodopa and Ferric maltol: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Oral iron binds levodopa in the gut, reducing its absorption and potentially lessening its effect, with worse motor control in some patients. This applies to oral ferric maltol.

O que esta interação significa em palavras simples

Carbidopa-levodopa and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Carbidopa-levodopa belongs to Central Nervous System; Ferric maltol belongs to Miscellaneous.

Nível de evidência: Moderate

Por que acontece

Chelation of levodopa by iron in the gastrointestinal tract, reducing absorption.

O que fazer

Separate doses by at least 2 hours and monitor motor response. Adjust the levodopa dose if symptoms worsen.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Carbidopa-levodopa with Ferric maltol?

MediHelp rates the interaction as moderate. Carbidopa-levodopa and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron binds levodopa in the gut, reducing its absorption and potentially lessening its effect, with worse motor control in some patients. This applies to oral ferric maltol.

How serious is the interaction between Carbidopa-levodopa and Ferric maltol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours and monitor motor response. Adjust the levodopa dose if symptoms worsen.

What other medicines interact with Carbidopa-levodopa?

MediHelp also lists interactions of Carbidopa-levodopa with, for example, Isocarboxazid, Phenelzine, Selegiline transdermal. The full list is on the Carbidopa-levodopa page.

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