Interações medicamentosas
Ethanol + Insulin degludec-liraglutide
Gravidade: Grave
Ethanol and Insulin degludec-liraglutide: major interaction.
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Resumo
Alcohol impairs hepatic gluconeogenesis and can cause severe, delayed hypoglycemia in insulin-treated patients, and can mask hypoglycemia symptoms. Heavy intake may also cause hyperglycemia from carbohydrate content.
O que esta interação significa em palavras simples
Ethanol and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Ethanol suppresses hepatic glucose production, adding to the glucose-lowering effect of insulin.
O que fazer
Advise intake only with food and in moderation, with frequent glucose monitoring including overnight and the next day. Counsel patients and companions on recognizing hypoglycemia.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Insulin degludec-liraglutide
Perguntas frequentes
Can I take Ethanol with Insulin degludec-liraglutide?
MediHelp rates the interaction as major. Ethanol and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Alcohol impairs hepatic gluconeogenesis and can cause severe, delayed hypoglycemia in insulin-treated patients, and can mask hypoglycemia symptoms. Heavy intake may also cause hyperglycemia from carbohydrate content.
How serious is the interaction between Ethanol and Insulin degludec-liraglutide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise intake only with food and in moderation, with frequent glucose monitoring including overnight and the next day. Counsel patients and companions on recognizing hypoglycemia.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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