Interações medicamentosas
Fludrocortisone + Mifepristone
Gravidade: Contraindicada
Fludrocortisone and Mifepristone: contraindicated interaction.
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Resumo
Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.
O que esta interação significa em palavras simples
Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Fludrocortisone belongs to Endocrine; Mifepristone belongs to Endocrine.
Por que acontece
Glucocorticoid receptor blockade reducing replacement efficacy
O que fazer
Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Fludrocortisone
- Aldesleukin + Fludrocortisone Grave
- Amphotericin b + Fludrocortisone Grave
- Bcg vaccine live + Fludrocortisone Grave
- Fludrocortisone + Influenza virus vaccine quadrivalent intranasal Grave
- Fludrocortisone + Measles mumps and rubella vaccine live Grave
- Fludrocortisone + Measles mumps rubella and varicella vaccine live Grave
Outras interações de Mifepristone
- Apixaban + Mifepristone Contraindicada
- Argatroban + Mifepristone Contraindicada
- Cisapride + Mifepristone Contraindicada
- Cortisone + Mifepristone Contraindicada
- Cyclosporin + Mifepristone Contraindicada
- Dabigatran etexilate + Mifepristone Contraindicada
Perguntas frequentes
Can I take Fludrocortisone with Mifepristone?
MediHelp rates the interaction as contraindicated. Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.
How serious is the interaction between Fludrocortisone and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.
What other medicines interact with Fludrocortisone?
MediHelp also lists interactions of Fludrocortisone with, for example, Aldesleukin, Amphotericin b, Bcg vaccine live. The full list is on the Fludrocortisone page.
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